The MOUSE ANTI BOVINE CD335:Low Endotoxin Antibody from MyBioSource.com is a Mouse Monoclonal antibody to CD335, LY94, NCR1, and NKp46. This antibody recognizes Bovine antigen. The MOUSE ANTI BOVINE CD335:Low Endotoxin Antibody has been validated for the following applications: Flow Cytometry, Functional Assay, Immunofluorescence, and Western Blot.
Description
Mouse anti Bovine CD335 antibody, clone AKS1 recognizes bovine CD335, also known as NKp46 and Natural cytotoxicity triggering receptor 1. CD335 is a type I transmembrane protein, with two extracellular C2-type immunoglobulin-like domains, which functions as an activating receptor. CD335 is expressed by human natural killer cells (Sivori et al. 1997). The bovine homologue is expressed on bovine NK cells (Storset et al. 2004) and no expression of CD335 has been detected on B cells, T cells, monocytes or granulocytes. Clone AKS1 is reported to activate lysis of FcgammaR-expressing cell line P815, by IL-2 activated NKp46+ cells (Storset et al. 2004)